Spread of impulse across synapse
Calcium gated channel in the presynaptic membrane opens when the nerve impulse arrives the synaptic knobCalcium ion diffuse quickly from the (synaptic cleft/ extracellular fluid) into the synaptic knob
The influx of calcium ion causes the synaptic vesicles to fuse with presynaptic membrane
The vesicles release neurotransmitter into the synaptic vesicle to fuse with presynaptic membrane
The vesicle release neurotransmitter
into the synaptic cleft by exocytosis
Neurotransmitter diffuse across the synaptic cleft & bind to the receptor on postsynaptic membrane
This triggers the sodium channel to open
Sodium ion diffuse into postsynaptic membrane , depolarising the postsynaptic membrane
A new potential is known as excitatory postsynaltic potential (EPSP)which is genrated if the EPSP is large enough to reach the threshold level
An action potential is generated
The action pptential is transmitted along the postsynaptic neurone
Spread of impulse across synapse (will be updated soon)
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